I am not sure what exactly Nintendo was thinking when they made Dr. Mario. The reason I was thinking about Dr. Mario was that I was playing it the other day and sucking it up on it as usual. For some reason girls seem to be better at this game then guys...just like Tetris as well. I think it is because they have better hand eye coordination. Anyway, here is the story of Dr. Mario...
He throws pills at viruses. Match the colored pills with the colored viruses. Repeat. Don't let your girlfriend/wife beat you.
For something more enjoyable, check out "What if Dr. Mario had lyrics?" by Internet sensation, brentalfloss.